5 Facts you should know about

Hereditary spastic paraplegia

A group of inherited diseases whose main feature is a progressive gait disorder

Early in the disease course, there may be mild gait difficulties and stiffness

Symptoms typically progress slowly so that eventually individuals with HSP may require the assistance of a cane, walker, or wheelchair

There are more than 80 different genetic types of HSP

The main feature of the disease is progressive spasticity in the lower limbs due to pyramidal tract dysfunction

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