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5 Facts every neurologist should know about
Tuberous sclerosis complex
About 70%–90% of individuals with tuberous sclerosis complex (TSC) will experience seizures at some point in their lives
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After just one seizure, patients living with TSC have a nearly 100% chance of developing recurring seizures
3
Skin findings are common in TSC and can include facial angiofibromas, hypomelanotic macules, and shagreen patches
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Brain involvement is almost universal in TSC, with cortical tubers, subependymal nodules, and subependymal giant cell astrocytomas (SEGAs) being the most common findings
5
Approximately 90% of patients living with TSC are affected by TSC-associated neuropsychiatric disorders (TAND), which may include behavioral difficulties, psychiatric disorders, and variations in intellectual ability
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