Rare Neurology News
Advertisement
5 Facts every neurologist should know about
Dravet syndrome
Hyperthermia triggers seizures in the majority of patients; other triggers may include flashing lights, visual patterns, bathing, eating, and overexertion
2
Children with Dravet syndrome often have developmental delays, cognitive impairment, and behavioral issues
3
Dravet syndrome is often accompanied by other neurological and physical problems, such as ataxia (lack of coordination), poor muscle tone, sleep disturbances, and respiratory issues
4
Treatment is challenging, primarily due to drug resistance of its seizures. Management often requires multiple anti-seizure medications (ASMs), a process further complicated by the potential for certain ASMs to worsen seizure activity
5
Patients typically receive multiple antiseizure medications, including valproate (VPA) and clobazam (CLB) initially, with options such as stiripentol (STP), cannabidiol (CBD), or fenfluramine (FFA) for escalated therapy