5 Facts you should know about

Centronuclear myopathy

Centronuclear myopathy (CNM) is an umbrella term for a group of rare genetic muscle disorders

The most notable clinical manifestations of CNM are muscle weakness and associated disabilities

Symptoms are often present at birth in the severe forms, but may first develop later in life, although onset in adulthood is unusual

CNMs derive their name based on the central location of the muscle fiber (muscle cell) nucleus---cell nuclei are abnormally located in the center of muscle cells instead of their normal location at the periphery

While some patients with centronuclear myopathies remain ambulatory throughout their adult life, others may never crawl or walk and may require wheelchair use for mobility

See our full disease profile

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