5 Facts you should know about

Arginase deficiency

Untreated children may exhibit seizures, spasticity, short stature and intellectual disability

Most affected infants are now identified at birth through newborn screening

Ammonia levels can vary according to the patient’s current age and status, presenting initially with reduction of growth and moving to milestone development and cognition

Most patients develop moderate to severe neurological damage, leading to poor quality of life

Chronic treatment consists of protein restriction along with nitrogen-scavenging medications

See our full disease profile

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