5 Facts you should know about

AL amyloidosis

AL amyloidosis is acquired and is caused by a small plasma cell clone that produces misfolded amyloidogenic light chains that deposit in different organs and tissues

Common sites for amyloid deposition include the skin, nerves, heart, gastrointestinal tract, kidneys, liver, spleen, and blood vessels

The most common associated conditions are nephrotic syndrome, heart failure, and peripheral neuropathy

Patients are often diagnosed only when severe organ damage is present

There is a significant inverse relationship between time of diagnosis after the onset of cardiac symptoms and 5-year survival

See our full disease profile

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