5 Facts you should know about

Adrenoleukodystrophy

Long chain fatty acid buildup causes damage to the myelin sheath of the nerves of the brain, resulting in seizures and hyperactivity

The most severely affected tissues are the myelin in the central nervous system, the adrenal cortex, and the Leydig cells in the testes

Approximately two-thirds of ALD patients will present with the childhood cerebral form of the disease, which is the most severe form

Initial symptoms in boys affected with the childhood cerebral form of ALD include emotional instability, hyperactivity, and disruptive behavior at school

The severe form is characterized by normal development in early childhood, followed by rapid degeneration to a vegetative state

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